The 20% rule: a simple, instantaneous radioactivity measurement defines cure and allows elimination of frozen sections and hormone assays during parathyroidectomy.

@article{Murphy1999The2R,
  title={The 20% rule: a simple, instantaneous radioactivity measurement defines cure and allows elimination of frozen sections and hormone assays during parathyroidectomy.},
  author={Colleen L Murphy and James C Norman},
  journal={Surgery},
  year={1999},
  volume={126 6},
  pages={1023-8; discussion 1028-9}
}
BACKGROUND Although primary hyperparathyroidism is a physiologic disease, surgeons rely on anatomical characteristics (gross and histologic) to determine appropriate operative decisions. After the development of radioguided parathyroidectomy, we hypothesized that the amount of radioactivity contained within resected tissue would be the only information needed to establish the nature of the tissue and to determine a cure for the disease. METHODS A total of 1290 tissue specimens were obtained… CONTINUE READING