The 2.5 Å Structure of the Enterococcus Conjugation Protein TraM resembles VirB8 Type IV Secretion Proteins*

@inproceedings{GoessweinerMohr2013The2,
  title={The 2.5 Å Structure of the Enterococcus Conjugation Protein TraM resembles VirB8 Type IV Secretion Proteins*},
  author={Nikolaus Goessweiner-Mohr and Lukas Grumet and Karsten Arends and Tea Pavkov-Keller and Christian C. Gruber and Karl Gruber and Ruth Birner-Gruenberger and Andrea Kropec-Huebner and Johannes Huebner and Elisabeth Grohmann and Walter Keller},
  booktitle={The Journal of biological chemistry},
  year={2013}
}
Conjugative plasmid transfer is the most important means of spreading antibiotic resistance and virulence genes among bacteria and therefore presents a serious threat to human health. The process requires direct cell-cell contact made possible by a multiprotein complex that spans cellular membranes and serves as a channel for macromolecular secretion. Thus far, well studied conjugative type IV secretion systems (T4SS) are of Gram-negative (G-) origin. Although many medically relevant pathogens… CONTINUE READING

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