• Corpus ID: 36131668

The 2-aminotetralin system as a structural base for new dopamine- and melatonin-receptor agents

@inproceedings{Copinga1994The2S,
  title={The 2-aminotetralin system as a structural base for new dopamine- and melatonin-receptor agents},
  author={Swier Copinga},
  year={1994}
}
The research described in this thesis is divided into two parts. Part I (chapters 1-3) deals with the development of a novel 2-aminotetralin as a mixed dopamine Dl/D2-receptor agonist, whereas part I1 (chapters 4-6) concerns the development of 2-amidotetralins as nonindolic melatonin-receptor agents. 
2 Citations

New, centrally acting dopaminergic agents with an improved oral bioavailability: synthesis and pharmacological evaluation

This chapter describes the synthesis and in vitro pharmacology of a novel series of dopamine receptor ligands, in which the classical phenylethylamine pharmacophore is replaced by a thienylethylamine

Impact of substituents on the enantioseparation of racemic 2‐amidotetralins on polysaccharide stationary phases. I. chiralcel OD

The direct enantiomeric separation of 32 racemic 2-amidotetralins on the commercially available tris-(3,5-dimethylphenylcarbamate) derivative of cellulose, coated on silica gel (Chiralcel OD), is

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