The -1082G/A polymorphism in IL-10 gene is associated with risk of Alzheimer's disease: a meta-analysis.

  title={The -1082G/A polymorphism in IL-10 gene is associated with risk of Alzheimer's disease: a meta-analysis.},
  author={Yong-gang Zhang and Jie Zhang and Can Tian and Yuling Xiao and Xiaobo Li and Chao He and Jin Huang and Hong Fan},
  journal={Journal of the neurological sciences},
  volume={303 1-2},
BACKGROUND The -1082G/A polymorphism in IL-10 gene has been extensively investigated for association to Alzheimer's disease (AD), however, results of different studies have been inconsistent. The objective of this study is to assess the relationship of IL-10 -1082G/A polymorphism and AD risk by using meta-analysis. METHODS All eligible case-control studies were searched in Pubmed and Embase. Odds ratios (OR) with the 95% confidence intervals (CI) were used to assess the association. RESULTS… CONTINUE READING

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