The 100-plus Study of cognitively healthy centenarians: rationale, design and cohort description

@inproceedings{Holstege2018The1S,
  title={The 100-plus Study of cognitively healthy centenarians: rationale, design and cohort description},
  author={Henne Holstege and Nina Beker and Tjitske Dijkstra and Karlijn Pieterse and Elizabeth Wemmenhove and Kimja Schouten and Linette Thiessens and Debbie Horsten and Sterre Rechtuijt and Sietske Sikkes and Frans W.A. van Poppel and Hanne Meijers-Heijboer and Marc Hulsman and Philip Scheltens},
  booktitle={European Journal of Epidemiology},
  year={2018}
}
Although the incidence of dementia increases exponentially with age, some individuals reach more than 100 years with fully retained cognitive abilities. To identify the characteristics associated with the escape or delay of cognitive decline, we initiated the 100-plus Study (www.100plus.nl). The 100-plus Study is an on-going prospective cohort study of Dutch centenarians who self-reported to be cognitively healthy, their first-degree family members and their respective partners. We collect… CONTINUE READING
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