The 100-kDa chain of nicein/kalinin is a laminin B2 chain variant.

@article{Vailly1994The1C,
  title={The 100-kDa chain of nicein/kalinin is a laminin B2 chain variant.},
  author={Jo{\"e}lle Vailly and Patrick Verrando and M F Champliaud and Donald R. Gerecke and D. W. Wagman and Christian Baudoin and D. Aberdam and Robert E. Burgeson and Elisabeth Bauer and Jean-paul Ortonne},
  journal={European journal of biochemistry},
  year={1994},
  volume={219 1-2},
  pages={209-18}
}
We have isolated the basement membrane component nicein and performed rotary-shadow analyses using electron microscopy that showed the presence of two forms (I and II) of the protein. Molecular cloning of the cDNA that codes for the 100-kDa chain of the protein revealed that the sequence matches those independently identified for the 105-155-kDa subunit of kalinin, a recently identified basement membrane component. These data demonstrate that nicein and kalinin contain an identical chain. The… CONTINUE READING