The 1.6 A crystal structure of the AraC sugar-binding and dimerization domain complexed with D-fucose.

Abstract

The crystal structure of the sugar-binding and dimerization domain of the Escherichia coli gene regulatory protein, AraC, has been determined in complex with the competitive inhibitor D-fucose at pH 5.5 to a resolution of 1.6 A. An in-depth analysis shows that the structural basis for AraC carbohydrate specificity arises from the precise arrangement of… (More)

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@article{Soisson1997The1A, title={The 1.6 A crystal structure of the AraC sugar-binding and dimerization domain complexed with D-fucose.}, author={Sean Soisson and B MacDougall-Shackleton and Ron Schleif and Cynthia Wolberger}, journal={Journal of molecular biology}, year={1997}, volume={273 1}, pages={226-37} }