The 1.4 angstrom crystal structure of the human oxidized low density lipoprotein receptor lox-1.

@article{Park2005The1A,
  title={The 1.4 angstrom crystal structure of the human oxidized low density lipoprotein receptor lox-1.},
  author={Hajeung Park and Floyd G Adsit and Jeffrey C. Boyington},
  journal={The Journal of biological chemistry},
  year={2005},
  volume={280 14},
  pages={13593-9}
}
The lectin-like oxidized low density lipoprotein receptor-1 (Lox-1) mediates the recognition and internalization of oxidatively modified low density lipoprotein by vascular endothelial cells. This interaction results in a number of pro-atherogenic cellular responses that probably play a significant role in the pathology of atherosclerosis. The 1.4 angstrom crystal structure of the extracellular C-type lectin-like domain of human Lox-1 reveals a heart-shaped homodimer with a ridge of six basic… CONTINUE READING
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