The (11;14)(q13;q32) translocation in multiple myeloma. A morphologic and immunohistochemical study.

@article{Hoyer2000TheT,
  title={The (11;14)(q13;q32) translocation in multiple myeloma. A morphologic and immunohistochemical study.},
  author={James D. Hoyer and Curtis A. Hanson and Rafael Silva da Fonseca and Philip R. Greipp and Gordon W. Dewald and Paul James Kurtin},
  journal={American journal of clinical pathology},
  year={2000},
  volume={113 6},
  pages={
          831-7
        }
}
We identified 24 cases of multiple myeloma with the t(11;14)(q13;q32). In 22 cases, the t(11;14)(q13;q32) was part of a complex karyotype, and in 2 cases it was an isolated abnormality. All patients had clinical and laboratory features consistent with multiple myeloma. The median degree of plasma cell involvement in the bone marrow was 60%, and in 10 cases, the plasma cells had a lymphoplasmacytoid appearance. Of the 24 cases, 21 had intermediate or high proliferative rates based on labeling… CONTINUE READING
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