The “adipose tissue expandability” hypothesis: a potential mechanism for insulin resistance in obese youth

@article{Caprio2018TheT,
  title={The “adipose tissue expandability” hypothesis: a potential mechanism for insulin resistance in obese youth},
  author={Sonia Caprio and Bridget M. Pierpont and Romy Kursawe},
  journal={Hormone Molecular Biology and Clinical Investigation},
  year={2018},
  volume={33}
}
Abstract Obesity has become a major global health challenge of the 21st century, as it is associated with the onset of type 2 diabetes (T2D) and cardiovascular complications, even at a very early age in life. The root causes of pediatric obesity remain incompletely understood. The obesity epidemic together with the relationship of obesity to the growing population burden of chronic disease presents unprecedented research opportunities and challenges. Decades of obesity-related research funded… 
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