The “Wow! signal” of the terrestrial genetic code

  title={The “Wow! signal” of the terrestrial genetic code},
  author={Vladimir I. Shcherbak and M. A. Makukov},

SETI in vivo: testing the we-are-them hypothesis

The seeded-Earth hypothesis is refresh in light of recent observations, the motivation for inserting a signature is discussed, and it is shown that ‘biological SETI’ involves even weaker assumptions than traditional SETI and admits a well-defined methodological framework.

The generation of meaningful information in molecular systems

  • P. Wills
  • Biology
    Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
  • 2016
The early phylogeny of the amino acyl-tRNA synthetase enzymes is discussed, leading to the conclusion that the observed optimality of the genetic code is a natural outcome of the processes of self-organization that produced it.

Euplotid: A quantized geometric model of the eukaryotic cell

TLDR is a quantized geometric model of the eukaryotic cell, an attempt at quantifying the incredible complexity that gives rise to a living cell by beginning from the smallest unit, a quanta.

Nucleotide tetramers TCGA and CTAG: viral DNA and the genetic code (hypothesis)

  • F. Filatov
  • Biology
    Journal of microbiology, epidemiology and immunobiology
  • 2022
A comparative analysis of CTAG and TCGA tetra-nucleotide FPs in viral DNAs suggests that these tetramers may have participated in the origin of the universal genetic code.

Evolution through the stochastic dyadic Cantor Set: the uniqueness of mankind in the Universe

  • D. Mahecha
  • Physics
    International Journal of Astrobiology
  • 2015
Abstract The search for intelligent life or any type of life involves processes with nonlinear chaotic behaviours throughout the Universe. Through the sensitive dependence condition, chaotic dynamics

Harmonic mean as a determinant of the genetic code

It is shown that there is a sense in splitting Genetic Code Table (GCT) into three parts using the harmonic mean, calculated by the formula H (a, b) = 2ab / (a + b), where a = 63 and b = 31.5. Within

Pulsar positioning system: a quest for evidence of extraterrestrial engineering

  • C. Vidal
  • Physics
    International Journal of Astrobiology
  • 2017
Abstract Pulsars have at least two impressive applications. First, they can be used as highly accurate clocks, comparable in stability to atomic clocks; secondly, a small subset of pulsars,

Hiding and Storing Messages and Data in DNA

  • V. Demidov
  • Computer Science, Biology
    DNA Beyond Genes
  • 2020
This work has shown that the ability to selectively amplify tiny amounts of DNA carrying an encoded or encrypted message or a label, and to read the DNA sequence in order to retrieve the DNA message (or DNA label) can be done automatically by special machines.

Advanced Panspermia

The proposed process of advanced panspermia includes the sending of animal embryos to Earth and the genetic modification of the human embryo that explains the mechanism of two critical milestones in the development of advanced life on Earth: the Cambrian explosion and the human brain.



Genetic code: Lucky chance or fundamental law of nature?

Origin and evolution of the genetic code: The universal enigma

Much of the evolution that led to the standard code could be a combination of frozen accident with selection for error minimization although contributions from coevolution of the code with metabolic pathways and weak affinities between amino acids and nucleotide triplets cannot be ruled out.

The Evolution of the Genetic Code Revisited

  • A. Travers
  • Biology
    Origins of Life and Evolution of Biospheres
  • 2006
A new set of parameters recently determined for B-DNA reveals that the codon–anticodon pairs for the codes in non-plant mitochondria on the one hand and prokaryotic and eukaryotic organisms on the other can be unequivocally divided into two classes – the most stable base steps define a common code specified by the first two bases in a codon while the less stable base Steps correlate with divergent usage and the adoption of a 3-letter code.

The Genetic Code Is One in a Million

It is concluded that the natural genetic code is extremely efficient at minimizing the effects of errors, but also that its structure reflects biases in these errors, as might be expected were the code the product of selection.

Order in the genetic code.

  • C. Woese
  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 1965
The question of "why codon assignments" is currently unanswered and therefore remains of prime interest, and the main reason for determining the set ofcodon assignments, or "codon catalogue," is that a knowledge of it may shed some light upon the mechanisms behind these particular assignments.

A colorful origin for the genetic code: Information theory, statistical mechanics and the emergence of molecular codes

  • T. Tlusty
  • Computer Science, Biology
    Physics of life reviews
  • 2010

The Darwinian Genetic Code: An Adaptation for Adapting?

  • S. Freeland
  • Biology
    Genetic Programming and Evolvable Machines
  • 2004
This work has suggested that the assignments of amino acids to codons appear to be organized so as to minimize the change in amino acid hydrophobicity that results from random mutations, and may in fact represent an adaptation to maximize the efficiency of adaptive evolution.

The Coevolution of Genes and Genetic Codes: Crick’s Frozen Accident Revisited

It is suggested that further affirmation of the role of coevolution can be attained by investigating the extent to which the outcome of coEVolution is robust to other influences that were present during the evolution of the code.

A four-column theory for the origin of the genetic code: tracing the evolutionary pathways that gave rise to an optimized code

A 'four-column' theory for the origin of the code is proposed that explains how the action of selection during the build-up of the codes leads to a final code that has the observed properties.

Selection, history and chemistry: the three faces of the genetic code.