The “Steroid Dementia Syndrome”: A Possible Model of Human Glucocorticoid Neurotoxicity

@article{Wolkowitz2007TheD,
  title={The “Steroid Dementia Syndrome”: A Possible Model of Human Glucocorticoid Neurotoxicity},
  author={Owen M. Wolkowitz and Sonia J. Lupien and Erin D. Bigler},
  journal={Neurocase},
  year={2007},
  volume={13},
  pages={189 - 200}
}
Glucocorticoid medications cause neurotoxicity in animals under certain circumstances, but it is not known if this occurs in humans. We present the case of a 10-year-old boy with no prior psychiatric history and no prior exposure to glucocorticoid medication who received a single 5-week course of glucocorticoids for an acute asthma flare. Beginning during steroid treatment, and persisting for over 3 years after stopping treatment, he showed a significant decline from his pre-morbid academic… 
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