The ‘entourage effect’ or ‘hodge-podge hashish’: the questionable rebranding, marketing, and expectations of cannabis polypharmacy
@article{Cogan2020TheE, title={The ‘entourage effect’ or ‘hodge-podge hashish’: the questionable rebranding, marketing, and expectations of cannabis polypharmacy}, author={P. Cogan}, journal={Expert Review of Clinical Pharmacology}, year={2020}, volume={13}, pages={835 - 845} }
ABSTRACT Introduction The concept of a cannabis ‘entourage effect’ was first coined as a hypothetical afterthought in 1998. Since then, multiple scientific reviews, lay articles, and marketing campaigns have promoted the effect as a wholly beneficial manifestation of polypharmacy expected to modulate the therapeutic effects of cannabis and its derivatives. There is reason to wonder at the authenticity of such claims. Areas covered A broad definition of the entourage effect is presented… CONTINUE READING
Topics from this paper
7 Citations
Reality and Legality: Disentangling What Is Actual from What Is Tolerated in Comparisons of Hemp Extracts with Pure CBD
- Business, Medicine
- Journal of dietary supplements
- 2020
- 2
Cannabis sativa Terpenes are Cannabimimetic and Provide Support for the Entourage Effect Hypothesis
- Biology, Chemistry
- 2020
- PDF
Practical Considerations of Hypotheses and Evidence in Cannabis Pharmacotherapy: Refining Expectations of Clinical Endocannabinoid Deficiency
- Psychology, Medicine
- Journal of dietary supplements
- 2020
- 1
Anti-Cancer Potential of Cannabinoids, Terpenes, and Flavonoids Present in Cannabis
- Medicine
- Cancers
- 2020
- 4
- PDF
Lack of evidence for the effectiveness or safety of over-the-counter cannabidiol products
- Business, Medicine
- Therapeutic advances in psychopharmacology
- 2020
- 1
- PDF
Differentiating Full-Spectrum Hemp Extracts from CBD Isolates: Implications for Policy, Safety and Science
- Biology, Medicine
- Journal of dietary supplements
- 2020
- 4
Neural Stem Cells and Cannabinoids in the Spotlight as Potential Therapy for Epilepsy
- Medicine
- International journal of molecular sciences
- 2020
- PDF
References
SHOWING 1-10 OF 79 REFERENCES
The Case for the Entourage Effect and Conventional Breeding of Clinical Cannabis: No “Strain,” No Gain
- Psychology, Medicine
- Front. Plant Sci.
- 2019
- 63
- PDF
On healthcare by popular appeal: critical assessment of benefit and risk in cannabidiol based dietary supplements
- Medicine
- Expert review of clinical pharmacology
- 2019
- 6
The Cannabis sativa Versus Cannabis indica Debate: An Interview with Ethan Russo, MD
- Medicine
- Cannabis and cannabinoid research
- 2016
- 64
- PDF
Appraising the “entourage effect”: Antitumor action of a pure cannabinoid versus a botanical drug preparation in preclinical models of breast cancer
- Medicine
- Biochemical pharmacology
- 2018
- 38
- PDF
Current Therapeutic Cannabis Controversies and Clinical Trial Design Issues
- Medicine
- Front. Pharmacol.
- 2016
- 58
- PDF
Practical considerations in medical cannabis administration and dosing.
- Medicine
- European journal of internal medicine
- 2018
- 142
- PDF
Recommendations From Cannabis Dispensaries About First-Trimester Cannabis Use.
- Medicine
- Obstetrics and gynecology
- 2018
- 65