The β-Amyloid Hypothesis in Alzheimer's Disease: Seeing Is Believing.

  title={The β-Amyloid Hypothesis in Alzheimer's Disease: Seeing Is Believing.},
  author={Hank F Kung},
  journal={ACS medicinal chemistry letters},
  volume={3 4},
Alzheimer's disease (AD) is a form of dementia that gradually worsens over time. The disease is not a part of normal aging, and it is likely caused by various processes that damage neurons of the brain. Many clinical symptoms are associated with AD, including cognitive decline, irreversible memory loss, disorientation, language impairment, etc. Major neuropathology observations of postmortem AD brain include the presence of senile plaquescontaining primarily β-amyloid (Aβ) peptide aggregates… CONTINUE READING
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