The α-linolenic acid content of flaxseed can prevent the atherogenic effects of dietary trans fat.

  title={The $\alpha$-linolenic acid content of flaxseed can prevent the atherogenic effects of dietary trans fat.},
  author={Chantal M. C. Bassett and Richelle S. McCullough and Andrea L. Edel and Amanda F Patenaude and Ren{\'e}e K. LaVall{\'e}e and Grant N Pierce},
  journal={American journal of physiology. Heart and circulatory physiology},
  volume={301 6},
Dietary intake of industrially hydrogenated trans fatty acids (TFA) has been associated with coronary heart disease. Dietary flaxseed can inhibit atherosclerosis induced by dietary cholesterol. The aim of this study was to determine whether supplementing the diet with flaxseed could protect against atherosclerosis induced by a diet enriched in TFA. Low-density lipoprotein receptor-deficient (LDLr(-/-)) mice were fed 1 of 14 experimental diets for 14 wk containing one of two fat sources [regular… 

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