The ß subunit of voltage-gated Ca2+ channels.

  title={The \ss subunit of voltage-gated Ca2+ channels.},
  author={Zafir Buraei and Jian Yang},
  journal={Physiological reviews},
  volume={90 4},
Calcium regulates a wide spectrum of physiological processes such as heartbeat, muscle contraction, neuronal communication, hormone release, cell division, and gene transcription. Major entryways for Ca(2+) in excitable cells are high-voltage activated (HVA) Ca(2+) channels. These are plasma membrane proteins composed of several subunits, including α(1), α(2)δ, β, and γ. Although the principal α(1) subunit (Ca(v)α(1)) contains the channel pore, gating machinery and most drug binding sites, the… CONTINUE READING
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