The ß-importin KAP8 (Pse1/Kap121) is required for nuclear import of the cellulase transcriptional regulator XYR1, asexual sporulation and stress resistance in Trichoderma reesei

@inproceedings{Ghassemi2015TheSSK,
  title={The \ss-importin KAP8 (Pse1/Kap121) is required for nuclear import of the cellulase transcriptional regulator XYR1, asexual sporulation and stress resistance in Trichoderma reesei},
  author={Sara Ghassemi and Alexander Lichius and Fr{\'e}d{\'e}rique Bidard and Sophie Lemoine and M. Rossignol and Silvia Herold and Verena Seidl-Seiboth and Bernhard Seiboth and Eduardo Antonio Espeso and Antoine Margeot and Christian Peter Kubicek},
  booktitle={Molecular microbiology},
  year={2015}
}
The ascomycete Trichoderma reesei is an industrial producer of cellulolytic and hemicellulolytic enzymes, and serves as a prime model for their genetic regulation. Most of its (hemi-)cellulolytic enzymes are obligatorily dependent on the transcriptional activator XYR1. Here, we investigated the nucleo-cytoplasmic shuttling mechanism that transports XYR1 across the nuclear pore complex. We identified 14 karyopherins in T. reesei, of which eight were predicted to be involved in nuclear import… CONTINUE READING
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