Corpus ID: 232105251

The `how' matters: A simulation-based assessment of the potential contributions of LFD tests for school reopening in England

  title={The `how' matters: A simulation-based assessment of the potential contributions of LFD tests for school reopening in England},
  author={K. Kunzmann and Camilla Lingjaerde and S. Bird and Sylvia Richardson},
During Covid-19 outbreaks, school closures are employed as part of governments’ nonpharmaceutical interventions around the world to reduce the number of contacts and keep the reproduction number below 1. Yet, prolonged school closures have profound negative impact on the future opportunities of pupils, particularly from disadvantaged backgrounds, as well as additional economic and social impacts by preventing their parents from returning to work. Data on Covid-19 in children are sparse and… Expand
1 Citations
Quantifying within-school SARS-CoV-2 transmission and the impact of lateral flow testing in secondary schools in England
Background To control within-school SARS-CoV-2 transmission in England, secondary school pupils have been encouraged to participate in twice weekly mass testing via lateral flow device tests (LFTs)Expand


Estimating the impact of reopening schools on the reproduction number of SARS-CoV-2 in England, using weekly contact survey data
It is suggested that reopening schools is likely to halt the fall in cases observed in recent months and risks returning to rising infections, but these estimates rely heavily on the current estimates or reproduction number and the current validity of the susceptibility and infectiousness profiles. Expand
OpenABM-Covid19 - an agent-based model for non-pharmaceutical interventions against COVID-19 including contact tracing
OpenABM-Covid19 is presented: an agent-based simulation of the epidemic including detailed age-stratification and realistic social networks and its Python interface has allowed scientists and policymakers to simulate dynamic packages of interventions and help compare options to suppress the COVID-19 epidemic. Expand
Returning to a normal life via COVID-19 vaccines in the USA: a large-scale agent-based simulation study
Although potent, vaccines alone cannot effectively end the pandemic given the current availability estimates and the adopted vaccination strategy, and non-pharmaceutical interventions need to continue and be enforced to ensure high compliance, so that the rate of immunity established by vaccination outpaces that induced by infections. Expand
Covid-19: Controversial rapid test policy divides doctors and scientists
The test missed infection in 60% of people, and most worryingly it missed 30% of those in people with very high viral loads, who are at the highest risk of spreading the virus to others. Expand
Covid-19: Lateral flow tests miss over half of cases, Liverpool pilot data show
The rapid test kits most widely used in UK universities, schools, and care homes detect just 48.89% of covid-19 infections in asymptomatic people when compared with a polymerase chain reaction (PCR)Expand
COVID-ABS: An agent-based model of COVID-19 epidemic to simulate health and economic effects of social distancing interventions
The COVID-ABS is a new SEIR (Susceptible-Exposed-Infected-Recovered) agent-based model that aims to simulate the pandemic dynamics using a society of agents emulating people, business and government and is a useful tool to assist politicians and health authorities to plan their actions against theCOVID-19 epidemic. Expand
Quantifying SARS-CoV-2 transmission suggests epidemic control with digital contact tracing
A mathematical model for infectiousness was developed to estimate the basic reproductive number R0 and to quantify the contribution of different transmission routes and the requirements for successful contact tracing, and the combination of two key parameters needed to reduce R0 to less than 1 was determined. Expand
Test sensitivity is secondary to frequency and turnaround time for COVID-19 screening
It is demonstrated that effective screening depends largely on frequency of testing and speed of reporting and is only marginally improved by high test sensitivity, and should prioritize accessibility, frequency, and sample-to-answer time. Expand
An analysis of SARS-CoV-2 viral load by patient age
A considerable percentage of infected people in all age groups, including those who are pre- or mild-symptomatic, carry viral loads likely to represent infectivity, and there is little evidence from the present study to support suggestions that children may not be as infectious as adults. Expand
Prevalence of Asymptomatic SARS-CoV-2 Infection
  • C. Elder
  • Medicine
  • Annals of Internal Medicine
  • 2021
This review and in particular its dubiously substantiated conclusion have been widely cited—including in many reports asserting that “up to 45% of all Covid-19 infections are from asymptomatic persons” (4)—and therefore urgently require correction. Expand