The "tail" of Connexin43: An unexpected journey from alternative translation to trafficking.

@article{Basheer2016TheO,
  title={The "tail" of Connexin43: An unexpected journey from alternative translation to trafficking.},
  author={Wassim A. Basheer and Robin Shaw},
  journal={Biochimica et biophysica acta},
  year={2016},
  volume={1863 7 Pt B},
  pages={1848-56}
}
With each heartbeat, Connexin43 (Cx43) cell-cell communication gap junctions are needed to rapidly spread and coordinate excitation signals for an effective heart contraction. The correct formation and delivery of channels to their respective membrane subdomain is referred to as protein trafficking. Altered Cx43 trafficking is a dangerous complication of… CONTINUE READING