The "muscle hypothesis" of chronic heart failure.

  title={The "muscle hypothesis" of chronic heart failure.},
  author={Andrew J S Coats},
  journal={Journal of molecular and cellular cardiology},
  volume={28 11},
Chronic heart failure is a well-recognized syndrome in which left ventricular impairment produces a constellation of secondary changes in other organ symptoms leading to symptoms such as muscular fatigue and dyspnoea and objective limitation to exercise tolerance. With modern drug therapy of diuretics and ACE inhibitors, the majority of patients have minimal if any signs of congestion, and yet severe symptomatic limitation remains. This limitation bears little relationship to conventional… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 52 extracted citations

Similar Papers

Loading similar papers…