The "interceptor" properties of chlorophyllin measured within the three-component system: intercalator-DNA-chlorophyllin.

@article{Pietrzak2006TheP,
  title={The "interceptor" properties of chlorophyllin measured within the three-component system: intercalator-DNA-chlorophyllin.},
  author={Monika Pietrzak and Zbigniew Wieczorek and Jolanta Wieczorek and Zbigniew Darzynkiewicz},
  journal={Biophysical chemistry},
  year={2006},
  volume={123 1},
  pages={11-9}
}
In aqueous solutions, in the presence of double-stranded DNA, chlorophyllin (CHL) forms complexes with each of the three DNA intercalators: acridine orange (AO), quinacrine mustard (QM), and doxorubicin (DOX). The evidence for these interactions was obtained by measurement changes in the absorption and fluorescence spectra of the mixtures containing DNA and intercalators during titration with CHL. A model of simple competition between DNA and CHL for the intercalator was used to define the… CONTINUE READING
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