Thawing Frozen Robust Multi-array Analysis (fRMA)

  title={Thawing Frozen Robust Multi-array Analysis (fRMA)},
  author={Matthew N. McCall and Rafael A. Irizarry},
  booktitle={BMC Bioinformatics},
A novel method of microarray preprocessing - Frozen Robust Multi-array Analysis (fRMA) - has recently been developed. This algorithm allows the user to preprocess arrays individually while retaining the advantages of multi-array preprocessing methods. The frozen parameter estimates required by this algorithm are generated using a large database of publicly available arrays. Curation of such a database and creation of the frozen parameter estimates is time-consuming; therefore, fRMA has only… CONTINUE READING
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The effect of GeneChip gene definitions on the microarray study of cancers

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