Thallium and cesium in muscle cells compete for the adsorption sites normally occupied by K+.

@article{Ling1977ThalliumAC,
  title={Thallium and cesium in muscle cells compete for the adsorption sites normally occupied by K+.},
  author={Gilbert Ning Ling},
  journal={Physiological chemistry and physics},
  year={1977},
  volume={9 3},
  pages={217-25}
}
It was shown that Tl+ can stoichiometrically displace K+ in frog muscle cells. This displacement is independent of the function of cell membrane and postulated pumps and of a macroscopic electric charge or Donnan effect. It follows that Cs+ and Tl+ compete for the adsorption sites normally occupied by K+. On this basis, the association-induction hypothesis predicts that Cs+ and Tl+, like K+, should be primarily localized in the A-band of the muscle myofibrils. 

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Maintenance of low Na+ and high K' levels in resting muscle cells: Na Pump theory vs. an effectively membrane-pumpless open-ended cell preparation

  • G N Ling
  • J . Physiol. (Lond.)
  • 1977

A Physical Theory of the Living State: The Associntion-Induction Hypothesis

  • G N Ling
  • A Physical Theory of the Living State: The…
  • 1962

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