Thallium-201 SPECT in advanced non-small cell lung cancer: in relation with chemotherapeutic response, survival, distant metastasis and p53 status.

@article{Cermik2003Thallium201SI,
  title={Thallium-201 SPECT in advanced non-small cell lung cancer: in relation with chemotherapeutic response, survival, distant metastasis and p53 status.},
  author={T. Cermik and Mahmut Y{\"u}ksel and Celal Karlikaya and Latife Doğanay and Mevl{\"u}t T{\"u}re and Sakir Berkarda},
  journal={Annals of nuclear medicine},
  year={2003},
  volume={17 5},
  pages={369-74}
}
PURPOSE The aim of this study was to evaluate the relationship between 201Tl tumor uptake, chemotherapeutic response, metastasis, p53 status and survival in non-small cell lung cancer (NSCLC). METHODS A total of 23 patients underwent 201Tl SPECT. In 9 patients, 2nd 201Tl SPECT study were performed 1 week after the 3rd cycle of chemotherapy (ChT), and early (ER) and delayed (DR) tumor/normal lung ratios and retention indices (RI) were obtained. In 15 patients p53 status was assayed with immuno… CONTINUE READING