Thalifaurine and dehydrodiscretine, new quaternary protoberberines from Thalictrum fauriei.

  title={Thalifaurine and dehydrodiscretine, new quaternary protoberberines from Thalictrum fauriei.},
  author={Christine Hiu-Tung Chen and T M Chen and C. J. Lee},
  journal={Journal of pharmaceutical sciences},
  volume={69 9},
  • C. Chen, T. Chen, C. Lee
  • Published 1 September 1980
  • Chemistry, Medicine
  • Journal of pharmaceutical sciences
Two new quaternary protoberberines, thalifaurine and dehydrodiscretine, were isolated from the ethanolic extract of Thalictrum fauriei Hayata. Based on spectral analysis and correlation with compounds of known structure, thalifaurine was shown to be 3-hydroxy-2-methoxy-10,11-methylenedioxyberbinium chloride and dehydrodiscretine was established as 3-hydroxy-2,20,11-trimethoxyberbinium chloride. The structural assignment was confirmed by synthesis of both compounds. Magnoflorine also was… 
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