Thalifaurine and dehydrodiscretine, new quaternary protoberberines from Thalictrum fauriei.

@article{Chen1980ThalifaurineAD,
  title={Thalifaurine and dehydrodiscretine, new quaternary protoberberines from Thalictrum fauriei.},
  author={Christine Hiu-Tung Chen and T M Chen and C. J. Lee},
  journal={Journal of pharmaceutical sciences},
  year={1980},
  volume={69 9},
  pages={
          1061-5
        }
}
  • C. Chen, T. Chen, C. Lee
  • Published 1 September 1980
  • Chemistry, Medicine
  • Journal of pharmaceutical sciences
Two new quaternary protoberberines, thalifaurine and dehydrodiscretine, were isolated from the ethanolic extract of Thalictrum fauriei Hayata. Based on spectral analysis and correlation with compounds of known structure, thalifaurine was shown to be 3-hydroxy-2-methoxy-10,11-methylenedioxyberbinium chloride and dehydrodiscretine was established as 3-hydroxy-2,20,11-trimethoxyberbinium chloride. The structural assignment was confirmed by synthesis of both compounds. Magnoflorine also was… 
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Alcaloïdes de l' Isopyrum thalictroïdes—bases quaternaires des feuilles—isolement et identification de quatre pseudoprotoberberines
TLDR
Four new protoberberines were isolated from leaves of Isopyrum thalictroides and the names pseudoberberine, pseudocoptisine, pseudocolumbamine and dehydropseudocheilanthifoline are proposed for them.
Die Alkaloide von Xylopia discreta (L. FIL.) SPRAGUEet HUTCHINS.
Aus der Rinde von Xylopia dicsreta (L. FIL.) SPRAGUEet HUTCHINS. sind folgende 5 kristallisierte Alkaloide isoliert worden: Xylopin (= O-Methylanolobin), Xylopinin(= (–)-Norcoralydin), Discretin (=
Total synthesis of (-)-discretine (2,10,11-trimethoxy-13a -berbin-3-ol).
(±)-Discretine (1) was obtained by a Mannich reaction of 1-(3,4-dimethoxybenzyl)-1,2,3,4-tetrahydro-6-hydroxy-7-methoxyisoquinoline with formalin. Optical resolution of (±)-discretine could not be