Thalidomide in newly diagnosed multiple myeloma and overview of experience in smoldering/indolent disease.

Abstract

Based on the activity of single-agent thalidomide demonstrated in relapsed or refractory multiple myeloma, investigators have evaluated the role of this agent in the treatment of earlier stage disease. Two key phase II trials of thalidomide plus dexamethasone in patients with previously untreated symptomatic multiple myeloma have yielded overall response… (More)

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