Thalidomide effects in Behçet's syndrome and pustular vasculitis.

@article{Jorizzo1986ThalidomideEI,
  title={Thalidomide effects in Behçet's syndrome and pustular vasculitis.},
  author={Joseph L. Jorizzo and Frank C. Schmalstieg and Alvin R. Solomon and Tito Cavallo and R. Stan Taylor and H Beth Rudloff and E J Schmalstieg and Jerry C. Daniels},
  journal={Archives of internal medicine},
  year={1986},
  volume={146 5},
  pages={
          878-81
        }
}
Pustular vasculitis is a new disease concept that links cutaneous, and possibly systemic, aspects of Behçet's, bowel bypass, bowel-associated dermatosis-arthritis, and disseminated gonorrhea syndromes. The pathomechanism of pustular vasculitic lesion generation may relate to circulating immune complex (CIC)-mediated vessel damage and serum enhancement of neutrophil migration. Thalidomide, an oral pharmaceutical available on strict protocol, has therapeutic effects based on proposed modulation… CONTINUE READING

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