Thalidomide-analogue biology: immunological, molecular and epigenetic targets in cancer therapy

Abstract

Thalidomide and its analogues (lenalidomide and pomalidomide) are small molecule glutamic acid derivatives of the immunomodulatory drug (IMiD) class. In addition to the immuno-adjuvant and anti-inflammatory properties that define an IMiD, the thalidomide analogues demonstrate an overlapping and diverse range of biological activities, including anti… (More)
DOI: 10.1038/onc.2012.599

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