Thalamocortical network activity enables chronic tic detection in humans with Tourette syndrome

@inproceedings{Shute2016ThalamocorticalNA,
  title={Thalamocortical network activity enables chronic tic detection in humans with Tourette syndrome},
  author={Jonathan B. Shute and Michael S. Okun and Enrico Opri and Rene Molina and Peter Justin Rossi and Daniel Martinez-Ramirez and Kelly Foote and Aysegul Gunduz},
  booktitle={NeuroImage: Clinical},
  year={2016}
}
Tourette syndrome (TS) is a neuropsychiatric disorder characterized by multiple motor and vocal tics. Deep brain stimulation (DBS) is an emerging therapy for severe cases of TS. We studied two patients with TS implanted with bilateral Medtronic Activa PC + S DBS devices, capable of chronic recordings, with depth leads in the thalamic centromedian-parafascicular complex (CM-PF) and subdural strips over the precentral gyrus. Low-frequency (1-10 Hz) CM-PF activity was observed during tics, as well… CONTINUE READING
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