Thalamocortical axons are influenced by chemorepellent and chemoattractant activities localized to decision points along their path.

@article{Braisted1999ThalamocorticalAA,
  title={Thalamocortical axons are influenced by chemorepellent and chemoattractant activities localized to decision points along their path.},
  author={Janet E. Braisted and R. Tuttle and D D O'leary},
  journal={Developmental biology},
  year={1999},
  volume={208 2},
  pages={430-40}
}
Thalamocortical axons (TCAs), which originate in dorsal thalamus, project ventrally in diencephalon and then dorsolaterally in ventral telencephalon to their target, the neocortex. To elucidate potentially key decision points in TCA pathfinding and hence the possible localization of guidance cues, we used DiI-tracing to describe the initial trajectory of TCAs in mice. DiI-labeled TCAs extend ventrally on the lateral surface of ventral thalamus. Rather than continuing this trajectory onto the… CONTINUE READING