Thalamic neuronal activity correlated with essential tremor.

  title={Thalamic neuronal activity correlated with essential tremor.},
  author={Sherwin E. Hua and Fred Lenz and T. Ali Zirh and Stephen G. Reich and Patrick M Dougherty},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  volume={64 2},
Animal studies suggest that an olivocerebello-bulbospinal pathway mediates harmaline induced tremor, which resembles essential tremor in humans. However, recent evidence suggests that thalamocortical pathways participate in essential tremor. Thalamic single neuron activity has been analysed during thalamotomy for essential tremor. It has been shown by spectral cross correlation analysis that thalamic activity has a significant, linear relation to forearm EMG activity during tremor. The presence… CONTINUE READING

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