Thalamic and prefrontal FDG uptake in never medicated patients with schizophrenia.

  title={Thalamic and prefrontal FDG uptake in never medicated patients with schizophrenia.},
  author={Douglas S Lehrer and Bradley T. Christian and Joseph C. Mantil and Aaron C Murray and Bradley R. Buchsbaum and Terrence R. Oakes and William Byne and Eileen M. Kemether and Monte S. Buchsbaum},
  journal={The American journal of psychiatry},
  volume={162 5},
OBJECTIVE Because neuroleptic treatment may cause long-lasting changes in brain structure and function, a group of patients with schizophrenia who had never been medicated was recruited to examine regional glucose metabolic rates in the frontal-striato-thalamic circuit. METHOD Twelve never medicated patients with schizophrenia (seven men, five women; mean age=29 years) and 13 normal volunteers (eight men and five women; mean age=28.5 years) underwent (18)F-fluorodeoxyglucose (FDG) positron… CONTINUE READING
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