Th22 and related cytokines in inflammatory and autoimmune diseases.

  title={Th22 and related cytokines in inflammatory and autoimmune diseases.},
  author={Tian Tian and Shuang Yu and Dao-xin Ma},
  journal={Expert opinion on therapeutic targets},
  volume={17 2},
INTRODUCTION Th22 and related cytokines regulate various processes and have been linked to diverse effects. The levels of Th22 and cytokine IL-22 are increased in several disorders and positively related to some autoimmune diseases. Preclinical studies have suggested that the inhibition or stimulation of IL-22 is an attractive approach to reverse the immune disorders. Simultaneously, considering many patients with refractory autoimmune diseases respond poorly to the therapies which are highly… CONTINUE READING

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