Th17 cells enhance viral persistence and inhibit T cell cytotoxicity in a model of chronic virus infection

Abstract

Persistent viral infection and its associated chronic diseases are a global health concern. Interleukin (IL) 17-producing Th17 cells have been implicated in the pathogenesis of various autoimmune diseases, and in protection from bacterial or fungal infection. However, the role of Th17 cells in persistent viral infection remains unknown. We report that Th17… (More)
DOI: 10.1084/jem.20082030

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