Th17 cell, the new player of neuroinflammatory process in multiple sclerosis.

@article{JadidiNiaragh2011Th17CT,
  title={Th17 cell, the new player of neuroinflammatory process in multiple sclerosis.},
  author={Farhad Jadidi-Niaragh and Abbas Mirshafiey},
  journal={Scandinavian journal of immunology},
  year={2011},
  volume={74 1},
  pages={1-13}
}
Multiple sclerosis (MS) is an autoimmune disease characterized by recurrent episodes of demyelination and axonal lesion mediated by CD4(+) T cells with a proinflammatory Th1 and Th17 phenotype, macrophages, and soluble inflammatory mediators. Identification of Th17 cells led to breaking the dichotomy of Th1/Th2 axis in immunopathogenesis of autoimmune diseases such as MS, and its experimental model, experimental autoimmune encephalomyelitis (EAE). Th17 cells are characterized by expression of… CONTINUE READING