Th17/Th1 biased immunity to the pneumococcal proteins PcsB, StkP and PsaA in adults of different age.

@article{Schmid2011Th17Th1BI,
  title={Th17/Th1 biased immunity to the pneumococcal proteins PcsB, StkP and PsaA in adults of different age.},
  author={Petra Schmid and Sanja Selak and Michael P. Keller and Barbara Luhan and Zolt{\'a}n Magyarics and Stefan Seidel and Petra Schlick and Christoph Reinisch and Karen Lingnau and Eszter Nagy and Beatrix Grubeck-Loebenstein},
  journal={Vaccine},
  year={2011},
  volume={29 23},
  pages={3982-9}
}
Streptococcus pneumoniae is a major human pathogen, causing high morbidity and mortality in children, and also in the elderly, who are particularly susceptible to S. pneumoniae infections due to the dysregulated function of the aged immune system. As the current generation of polysaccharide vaccines do not provide sufficient protection for elderly, new vaccination strategies are urgently needed. To learn whether pneumococcal proteins are able to induce adaptive immune responses in adults in… CONTINUE READING
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