Th1-Th2: reliable paradigm or dangerous dogma?

@article{Allen1997Th1Th2RP,
  title={Th1-Th2: reliable paradigm or dangerous dogma?},
  author={Judith E Allen and Rick M. Maizels},
  journal={Immunology today},
  year={1997},
  volume={18 8},
  pages={
          387-92
        }
}
Abstract The identification of crossregulating T helper (Th) cells has revolutionized current understanding of the immune response to infection. While paying tribute to this revolution, Judith Allen and Rick Maizels argue that the paradigm can be dangerously oversimplified and that the interaction between host and pathogen cannot always be addressed in the context of Th1 and Th2 cells. 

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