Th1/Th2/Th17/Treg cytokine imbalance in systemic lupus erythematosus (SLE) patients: Correlation with disease activity.

@article{Talaat2015Th1Th2Th17TregCI,
  title={Th1/Th2/Th17/Treg cytokine imbalance in systemic lupus erythematosus (SLE) patients: Correlation with disease activity.},
  author={Roba M Talaat and Sara F Mohamed and Iman Hamed Bassyouni and Ahmed M. Abdel Raouf},
  journal={Cytokine},
  year={2015},
  volume={72 2},
  pages={146-53}
}
AIM Imbalance of T-helper-cell (TH) subsets (TH1/TH2/TH17) and regulatory T-cells (Tregs) is suggested to contribute to the pathogenesis of Systemic lupus erythematosus (SLE). Therefore, we evaluated their cytokine secretion profile in SLE patients and their possible association with disease activity. METHODS Sixty SLE patients, 24 rheumatoid arthritis (RA) patients and 24 healthy volunteers were included in this study. Demographic, clinical, disease activity and serological data were… CONTINUE READING
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