Text S1. Methods (full Version). 1 Structure of Data 2 General Framework for Inference


    The analysis presented is based on the HR events previously described by Croucher et al. (2011). Briefly, that analysis identified M independent HR events as clusters of SNPs in a genealogy reconstructed from N whole genome alignments of the PMEN1 lineage. The reconstructed genealogy has B branches. Let i = 1, ..., B label the branches, and let m i be the… (More)


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