Teuvincenone F Suppresses LPS-Induced Inflammation and NLRP3 Inflammasome Activation by Attenuating NEMO Ubiquitination

@inproceedings{Zhao2017TeuvincenoneFS,
  title={Teuvincenone F Suppresses LPS-Induced Inflammation and NLRP3 Inflammasome Activation by Attenuating NEMO Ubiquitination},
  author={Xibao Zhao and Debing Pu and Zizhao Zhao and Huihui Zhu and Hongrui Li and Yaping Shen and Xingjie Zhang and Ruihan Zhang and Jianzhong Shen and Wei-Lie Xiao and Weilin Chen},
  booktitle={Front. Pharmacol.},
  year={2017}
}
Inflammation causes many diseases that are serious threats to human health. However, the molecular mechanisms underlying regulation of inflammation and inflammasome activation are not fully understood which has delayed the discovery of new anti-inflammatory drugs of urgent clinic need. Here, we found that the natural compound Teuvincenone F, which was… CONTINUE READING