Tetrodotoxin-sensitive persistent current boosts the depolarization of retinal amacrine cells in goldfish

@article{Watanabe2000TetrodotoxinsensitivePC,
  title={Tetrodotoxin-sensitive persistent current boosts the depolarization of retinal amacrine cells in goldfish},
  author={Sayaka Watanabe and Hiromasa Satoh and Amane Koizumi and Tetsuya Takayanagi and Akimichi Kaneko},
  journal={Neuroscience Letters},
  year={2000},
  volume={278},
  pages={97-100}
}
To light illumination retinal amacrine cells respond with graded depolarization accompanied by a spike discharge. It has been assumed that the graded depolarization is produced solely by the excitatory synaptic inputs from bipolar cells. Here we demonstrate that a tetrodotoxin (TTX)-sensitive persistent current also contributes to the graded depolarization. This current was isolated in amacrine cells of the goldfish retinal slice preparations by the whole-cell patch clamp technique. The… CONTINUE READING
BETA

From This Paper

Topics from this paper.

Similar Papers

Loading similar papers…