Tetrodotoxin-sensitive and -resistant Na+ channel currents in subsets of small sensory neurons of rats.

@article{Wu2004TetrodotoxinsensitiveA,
  title={Tetrodotoxin-sensitive and -resistant Na+ channel currents in subsets of small sensory neurons of rats.},
  author={Zi-Zhen Wu and H. I. Pan},
  journal={Brain research},
  year={2004},
  volume={1029 2},
  pages={251-8}
}
Voltage-activated Na+ channels in the primary sensory neurons are important for generation of action potentials and regulation of neurotransmitter release. The Na+ channels expressed in different types of dorsal root ganglion (DRG) neurons are not fully known. In this study, we determined the possible difference in tetrodotoxin-sensitive (TTX-S) and -resistant (TTX-R) Na+ channel currents between isolectin B4 (IB4)-positive and IB4-negative small DRG neurons. Whole-cell voltage- and current… CONTINUE READING