Tetrodotoxin-resistant voltage-gated sodium channels Na(v)1.8 and Na(v)1.9 are expressed in the retina.

@article{OBrien2008TetrodotoxinresistantVS,
  title={Tetrodotoxin-resistant voltage-gated sodium channels Na(v)1.8 and Na(v)1.9 are expressed in the retina.},
  author={Brendan Joseph O'Brien and John H. Caldwell and George R. Ehring and Keely M Bumsted O'Brien and Songjiang Luo and Simon Rock Levinson},
  journal={The Journal of comparative neurology},
  year={2008},
  volume={508 6},
  pages={
          940-51
        }
}
Voltage-gated sodium channels (VGSCs) are one of the fundamental building blocks of electrically excitable cells in the nervous system. These channels are responsible for the generation of action potentials that are required for the communication of neuronal signals over long distances within a cell. VGSCs are encoded by a family of nine genes whose products have widely varying biophysical properties. In this study, we have detected the expression of two atypical VGSCs (Na(v)1.8 and Na(v)1.9… CONTINUE READING

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