Tetrodotoxin-resistant Na+ spikes of C fibers have at least two subtypes in the isolated bullfrog sciatic nerve.

@article{Kobayashi1996TetrodotoxinresistantNS,
  title={Tetrodotoxin-resistant Na+ spikes of C fibers have at least two subtypes in the isolated bullfrog sciatic nerve.},
  author={Jun'ichi Kobayashi and Masayasu Ohta and Yoshihiro Terada},
  journal={Neuroscience letters},
  year={1996},
  volume={221 1},
  pages={
          9-12
        }
}
The C fiber compound action potentials (C-CAPs) were studied for their properties with the vaseline gap method from the isolated bullfrog sciatic nerve. Two components (the fast and the slow C-CAPs) were found to be Na+ dependent and tetrodotoxin-resistant. The conduction velocities of the fast and the slow C-CAPs were 0.61 +/- 0.06 m/s (n = 13) and 0.42 +/- 0.05 m/s (n = 8), respectively; their time constants were 11.4 +/- 1.7 m/s and 16.3 +/- 1/7 ms, respectively, with both parameters being… CONTINUE READING