Tetrazepam drug sensitivity − usefulness of the patch test

  title={Tetrazepam drug sensitivity − usefulness of the patch test},
  author={C. Pirker and Ana M Misic and T. Brinkmeier and P. Frosch},
  journal={Contact Dermatitis},
  • C. Pirker, Ana M Misic, +1 author P. Frosch
  • Published 2002
  • Medicine
  • Contact Dermatitis
  • The muscle relaxant tetrazepam may cause severe cutaneous adverse effects. We report 4 cases of varying intensity: Stevens–Johnson syndrome, erythema–multiforme‐like exanthema, maculopapular and maculo‐urticarial exanthema. Patch testing with tetrazepam (10% in petrolatum) was strongly positive in the 2 patients with severe skin eruptions and weakly positive in the other 2. Oral rechallenge with tetrazepam was positive in 3 patients (1 not done). Diazepam, with a similar chemical structure to… CONTINUE READING
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