• DOI:10.1111/j.1600-0536.1992.tb00259.x
• Corpus ID: 43750783

Tetrazepam allergy once more detected by patch test

@article{Collet1992TetrazepamAO,
  title={Tetrazepam allergy once more detected by patch test},
  author={Evelyne Collet and Sophie Dalac and Chu Morvan and Catherine Sgro and D G Lambert},
  journal={Contact Dermatitis},
  year={1992},
  volume={26}
}

• E. Collet, S. Dalac, +2 authors D. Lambert
• Published 1 April 1992
• Medicine
• Contact Dermatitis

In February 1989, a 63-year-old man, with lumbar intervertebral degenerative arthritis, presented with maculopapular to purpuric lesions on the legs, which had appeared some days after the prescription of tetrazepam (Myolastan®), paracetamol (Efferalgan®) and intra-articular prednisolone (HydrocortancyJ®). Histologic study showed leucocytoclastic vasculitis with some deposits of C!Q, C3 and IgM on direct immunofluorescence. 2 days after treatment was discontinued, the lesions started to disappear. 3 months later, prick tests, patch tests (Finn Chambers) and IDR were negative with HydrocortancyJ®. Patch testing to 1% Myolastan was positive ( + +) at 2 and 3 days. A similar reaction was observed to tetrazepam 1% pet. ( + + ), but the excipients were negative. I month later, an unintended prescription of paracetamol produced no side-effects.