Tetratricopeptide-motif-mediated interaction of FANCG with recombination proteins XRCC3 and BRCA2.

@article{Hussain2006TetratricopeptidemotifmediatedIO,
  title={Tetratricopeptide-motif-mediated interaction of FANCG with recombination proteins XRCC3 and BRCA2.},
  author={Shobbir Hussain and James B. Wilson and Eric Blom and Larry H. Thompson and Patrick Sung and Susan M Gordon and Gary M. Kupfer and Hans Joenje and Christopher G Mathew and Nigel Jones},
  journal={DNA repair},
  year={2006},
  volume={5 5},
  pages={629-40}
}
Fanconi anaemia is an inherited chromosomal instability disorder characterised by cellular sensitivity to DNA interstrand crosslinkers, bone-marrow failure and a high risk of cancer. Eleven FA genes have been identified, one of which, FANCD1, is the breast cancer susceptibility gene BRCA2. At least eight FA proteins form a nuclear core complex required for… CONTINUE READING