Tetrasulfated disaccharide unit in heparan sulfate: enzymatic formation and tissue distribution.

@article{Mochizuki2008TetrasulfatedDU,
  title={Tetrasulfated disaccharide unit in heparan sulfate: enzymatic formation and tissue distribution.},
  author={Hideo Mochizuki and Keiichi Yoshida and Yuniko Shibata and Koji Kimata},
  journal={The Journal of biological chemistry},
  year={2008},
  volume={283 45},
  pages={31237-45}
}
We previously reported that the heparan sulfate 3-O-sulfotransferase (3OST)-5 produces a novel component of heparan sulfate, i.e. the tetrasulfated disaccharide (Di-tetraS) unit ( Mochizuki, H., Yoshida, K., Gotoh, M., Sugioka, S., Kikuchi, N., Kwon, Y.-D., Tawada, A., Maeyama, K., Inaba, N., Hiruma, T., Kimata, K., and Narimatsu, H. (2003) J. Biol. Chem. 278, 26780-26787 ). In the present study, we investigated the potential of other 3OST isoforms to produce Di-tetraS with heparan sulfate and… CONTINUE READING
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NUMBER 45 JOURNAL OF BIOLOGICAL CHEMISTRY 31245 by gest on Jne 24

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