Tetraspanins: push and pull in suppressing and promoting metastasis

@article{Zller2009TetraspaninsPA,
  title={Tetraspanins: push and pull in suppressing and promoting metastasis},
  author={M. Z{\"o}ller},
  journal={Nature Reviews Cancer},
  year={2009},
  volume={9},
  pages={40-55}
}
  • M. Zöller
  • Published 2009
  • Biology, Medicine
  • Nature Reviews Cancer
  • Tumours progress through a cascade of events that enable the formation of metastases. Some of the components that are required for this fatal process are well established. Tetraspanins, however, have only recently received attention as both metastasis suppressors and metastasis promoters. This late appreciation is probably due to their capacity to associate with various molecules, which they recruit into special membrane microdomains, and their abundant presence in tumour-derived small vesicles… CONTINUE READING
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