Tetraphenylboron Causes Ca 2 + Release in Isolated Sarcoplasmic Reticulum and in Skinned Muscle Fibers

@inproceedings{ShoshanS2001TetraphenylboronCC,
  title={Tetraphenylboron Causes Ca 2 + Release in Isolated Sarcoplasmic Reticulum and in Skinned Muscle Fibers},
  author={Varda ShoshanS and Donald and Woodl},
  year={2001}
}
  • Varda ShoshanS, Donald, Woodl
  • Published 2001
The lipophilic anion tetraphenylboron (TPB-) but not the lipophilic cation tetraphenylarsonium (“PA+) inhibited ATP-dependent Ca2+ accumulation by isolated sarcoplasmic reticulum. TPBdid not inhibit ATP hydrolysis but did induce Ca2+ release from preloaded vesicles. It did not appear to disrupt lipid bilayers or to act as a Ca2+ ionophore since it had no… CONTINUE READING